Professional astronomy is split into observational and theoretical branches. Observational astronomy is focused on acquiring data from observations of astronomical objects. This data is then analyzed using basic principles of physics. Theoretical astronomy is oriented toward the development of computer or analytical models to describe astronomical objects and phenomena. These two fields complement each other. Theoretical astronomy seeks to explain observational results and observations are used to confirm theoretical results.
Its great advances notwithstanding, astronomy is still subject to a major constraint: it is inherently an observational rather than an experimental science. Almost all measurements must be performed at great distances from the objects of interest, with no control over such quantities as their temperature, pressure, or chemical composition. There are a few exceptions to this limitation—namely, meteorites (most of which are from the asteroid belt, though some are from the Moon or Mars), rock and soil samples brought back from the Moon, samples of comet and asteroid dust returned by robotic spacecraft, and interplanetary dust particles collected in or above the stratosphere. These can be examined with laboratory techniques to provide information that cannot be obtained in any other way. In the future, space missions may return surface materials from Mars, or other objects, but much of astronomy appears otherwise confined to Earth-based observations augmented by observations from orbiting satellites and long-range space probes and supplemented by theory.

Theoretical astronomers use several tools including analytical models and computational numerical simulations; each has its particular advantages. Analytical models of a process are better for giving broader insight into the heart of what is going on. Numerical models reveal the existence of phenomena and effects otherwise unobserved.
Theorists in astronomy endeavor to create theoretical models and from the results predict observational consequences of those models. The observation of a phenomenon predicted by a model allows astronomers to select between several alternate or conflicting models as the one best able to describe the phenomena.
Theorists also try to generate or modify models to take into account new data. In the case of an inconsistency between the data and the model's results, the general tendency is to try to make minimal modifications to the model so that it produces results that fit the data. In some cases, a large amount of inconsistent data over time may lead to the total abandonment of a model.
Phenomena modeled by theoretical astronomers include: stellar dynamics and evolution; galaxy formation; large-scale distribution of matter in the Universe; origin of cosmic rays; general relativity and physical cosmology, including string cosmology and astroparticle physics. Astrophysical relativity serves as a tool to gauge the properties of large scale structures for which gravitation plays a significant role in physical phenomena investigated and as the basis for black hole (astro)physics and the study of gravitational waves.
Some widely accepted and studied theories and models in astronomy, now included in the Lambda-CDM model are the Big Bang, dark matter and fundamental theories of physics.